The star has donated the entirety of his £25k Mercury Prize cash to the MVT, which functions to preserve the UK's independent music venues.
Fender was given the prize on 16 October as his third album the album was named the best record of the previous year.
Fender has decided to donate the funds to the Music Venues Trust, in appreciation of the vital role small stages played in his early career.
"I personally would not have achieved this success if it hadn't been for all the performances I did around the region, and beyond, when I was starting out," remarked Fender. "These locations are renowned, but they are facing challenges."
From early 2023 onward, more than 150 of these venues have shut down – roughly 16 percent of the entire UK sector.
In the last year, well-known musicians like Pulp, Coldplay, the singer Katy Perry and Ed Sheeran have all backed the Music Venues Trust in its initiatives to help venues survive, by including a modest fee to their admission fees, which goes to help smaller concert halls.
Sam Fender also joined in, collecting in excess of £100,000 on his recent tour to support 38 small stages across Britain.
These funds helped venues that were confronting possible closure due to challenges stemming from water damage, fire incidents and personal losses, as well as regulatory hurdles, legal disputes and noise complaints.
Some locations obtained funding support in upgrading infrastructure and sound and lighting systems that directly benefitted performers and concertgoers.
"The notion that funds from concerts in major spaces supports the smaller venues, where it all starts for artists like me, is just sensible," Sam Fender has commented.
The musician is among several artists to give his award prize money to charitable organizations.
In Pulp won the trophy in the mid-90s for their release Different Class, vocalist Jarvis Cocker stated that the band would donate their prize money to the organization War Child.
In 2002, rapper and singer she split her bounty among multiple charities, including the children's charity and a Sickle Cell charity.
"Additionally, I donated a thousand pounds to Highgate Newtown, to their classes, because I trained in gymnastics when I was a child and they needed updated gear," Ms Dynamite shared with a publication.
Previously, they gave their winnings to the local youth club that nurtured their act, in addition to other local music groups.
Additionally 1994 winners the group gave their prize to a multiple sclerosis charity after a close contact was found to have the condition.
"The victory was quite enough," stated vocalist Small. "The money was the extra but we didn't need the extra, because we had the cake. So our winning affected another person's life."
In the past week, the Music Venues Trust shared it had saved a couple of local spots in that region, by bringing them into local control.
The Joiners in Southampton and the other in that location were bought under the public acquisition initiative, which is supported by the arts council and enthusiasts who acquire "stakes" in the venues.